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    API and related Intermediates

    • Product:Prostaglandin Latanoprost
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      • Prostaglandin Latanoprost
    Product information
    NameAlprostadil
    Structure Prostaglandin Latanoprost; 130209-82-4
    Other nameLatanoprost; 130209-82-4
    CAS NO.130209-82-4
    Molecular FormulaC26H40O5
    Molecular Weight432.601 g/mol





    TEST

    SPECIFICTIONS

    TEST RESULTS

    Appearance

    Colorless or light yellow oil

    Complies

    Identification

    IR of the sample should match with standard

    Complies

    RT of sample should match with standard in the

    Related substances

    Complies

    Optical rotation

    +31°~ +38°

    +36°

    Water content

    2.0%

    0.05%

    Residue on ignition

    0.5%

    0.06%

    Isopropyl diphenyl-

    phosphorylpentanoate

     

    0.1%

    0.02%

    Related Compound B

    (15S-cis isomer)

    0.5%

    0.15%

    Related Compound A

    (5,6-trans isomer)

    3.5%

    0.21%

    Related Compound E

    (Latanoprost acid)

    0.2%

    N.D

    Other max single impurity

    0.1%

    N.D

    Total impurities

    0.5%

    N.D

    Residue solvents

    Acetone0.5%

    N.D

    Methanol0.3%

    N.D

    Toluene0.089%

    N.D

    Tetrahydrofuran0.072%

    N.D

    Ethyl acetate0.5%

    0.09%

    Dichloromethane0.06%

    N.D

    Assay

    94%~102%

    99.52%

    Conclusion:

    Complies with USP Standard 


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    Tag:cas 130209-82-4

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